(S)-WAY-100135 (hydrochloride), CAS 149007-54-5

Formulation: A solid

Formal Name: (αS)-N-(1,1-dimethylethyl)-4-(2-methoxyphenyl)-α-phenyl-1-piperazinepropanamide, dihydrochloride

Purity: ≥98%

Formula Markup: C24H33N3O2 • 2HCl

Formula Weight: 468,5

Shelf life (days): 1460

CAS Number: 149007-54-5

Notes: (S)-WAY-100135 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50 = 15.5 nM in a radioligand binding assay using rat hippocampus).{58220} It is selective for 5-HT1A over 5-HT1B, 5-HT1C, and 5-HT2 receptors, as well as dopamine D1 and D2, and α1-, α2-, and β-adrenergic receptors (IC50s = >1 µM for all).{58219} (S)-WAY-100135 (10 mg/kg) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice, indicating anxiolytic-like activity.{58219}

• Artikelnummer: CAY32851-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 32851-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK