Formulation: A crystalline solid
Formal Name: 7-(acetyloxy)-5-chloro-3-[(1E,3E,5S)-3,5-dimethyl-1,3-heptadien-1-yl]-7-methyl-6H-2-benzopyran-6,8(7H)-dione
Purity: ≥98%
Formula Markup: C21H23ClO5
Formula Weight: 390,9
Shelf life (days): 1460
CAS Number: 549-23-5
Notes: Sclerotiorin is a natural product isolated primarily from Penicillium species. It inhibits soybean lipoxygenase-1 with an IC50 value of 4.2 µM.{15873} Sclerotiorin also exhibits a number of other activities including inhibition of cholesterol ester transfer protein (IC50 = 19.4 µM),{10419}, inhibition of Grb2-Shc interaction (IC50 = 22 µM),{16817}, and antagonism of endothelin receptors (IC50 = 114 and 152 µM for human ETA and ETB, respectively).{16816}