SER-601, CAS 1048038-90-9

Formulation: A crystalline solid

Formal Name: 1,4-dihydro-6-(1-methylethyl)-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-3-quinolinecarboxamide

Purity: ≥98%

Formula Markup: C28H38N2O2

Formula Weight: 434,6

Shelf life (days): 730

CAS Number: 1048038-90-9

Notes: SER-601 is a potent and selective peripheral cannabinoid (CB2) receptor agonist with 190-fold selectivity for CB2 over the central CB1 receptor (Kis = 6.3 and 1,220 nM, respectively).{20869,20870} At 3 mg/kg, SER-601 has analgesic effects in a formalin-induced nocifensive study in mice without cannabis-like behavioral effects due to its low affinity for the CB1 receptor.{20869,20870} SER-601 also has antidiabetic effects.{35108} Two to four week exposure to SER-601 ameliorates insulin resistance in vivo and increases insulin secretion and accumulation in pancreatic islets isolated from high-fat diet/streptozotocin (HFD/STZ)-induced diabetic mice.

• Artikelnummer: CAY11743-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11743-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe