Formulation: A crystalline solid
Formal Name: 2-methoxy-5,6-dimethyl-9(10H)-acridinone
Purity: ≥98%
Formula Markup: C16H15NO2
Formula Weight: 253,3
Shelf life (days): 730
CAS Number: 2411100-70-2
Notes: STING agonist 12b is an agonist of stimulator of interferon genes (STING).{59528} It binds to STING (Kd = 26.4 µM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 µM, respectively). STING agonist 12b (40 µM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.