Formulation: A crystalline solid
Formal Name: 2-[3-chloro-4-(1,1-dimethylethyl)phenyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-fluoro-1,2,3,4-tetrahydro-1-oxo-4-isoquinolineacetic acid
Purity: ≥98%
Formula Markup: C29H27ClFNO5
Formula Weight: 524
Shelf life (days): 730
CAS Number: 2706536-26-5
Notes: STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 µM in a radioligand binding assay).{35985} It inhibits cGAMP-induced IFN-β production (IC50 = 11 µM) but does not stimulate IFN-β production (EC50 = >30 µM) in THP-1 cells.