Succinylcholine (chloride hydrate), CAS 6101-15-1

Formulation: A crystalline solid

Formal Name: 2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-ethanaminium, dichloride, dihydrate

Purity: ≥95%

Formula Markup: C14H30N2O4 • 2Cl [2H2O]

Formula Weight: 397,3

Shelf life (days): 1460

CAS Number: 6101-15-1

Notes: Succinylcholine is an agonist of muscle-type nicotinic acetylcholine receptors (nAChRs).{52931} It activates the muscle-type α1β1δε subunit-containing nAChR (EC50 = 10.8 µM in X. laevis oocytes expressing the human receptor) then induces desensitization of the receptor. It is selective for the muscle-type nAChR over α3β2, α3β4, α4β2, or α7 subunit-containing neuronal nAChRs (IC50s = >100 µM). Succinylcholine (600 µg) induces neuromuscular block in isolated rat phrenic nerve-diaphragm preparations stimulated via the phrenic nerve.{52932} Formulations containing succinylcholine have been used as an adjunct to general anesthesia for its muscle relaxant properties.

• Artikelnummer: CAY32829-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 32829-25
• Green Labware: Nein
• Verpackungseinheit: 25 g
• Mengeneinheit: STK