Swertisin, CAS 6991-10-2

Formulation: A solid

Formal Name: 6-β-D-glucopyranosyl-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C22H22O10

Formula Weight: 446,4

Shelf life (days): 1460

CAS Number: 6991-10-2

Notes: Swertisin is a flavonoid C-glycoside that has been found in Swertia japonica and has diverse biological activities.{61674,61675,61676} It inhibits sodium-glucose cotransporter 2 (SGLT2) in HEK293 cells when used at a concentration of 7.5 µg/ml and is an adenosine A1 receptor antagonist (IC50 = 137 µM).{61674,61675} Swertisin (0.2-5 µM) inhibits hepatitis B virus (HBV) replication in HepG2 2.2.15 cells.{61676} It decreases blood glucose levels in a mouse model of diabetes induced by streptozotocin (Item No. 13104), as well as prevents scopolamine-induced increases in escape latency in the Morris water maze in mice.{61674,61675}

• Artikelnummer: CAY34744-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34744-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK