Tasimelteon-d5, CAS 1962124-51-1

Formulation: A solid

Formal Name: N-[[(1R,2R)-2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]methyl]-propanamide-2,2,3,3,3-d5

Purity: ≥99% deuterated forms (d1-d5)

Formula Markup: C15H14D5NO2

Formula Weight: 250,4

Shelf life (days): 1460

CAS Number: 1962124-51-1

Notes: Tasimelteon-d5 is intended for use as an internal standard for the quantification of tasimelteon (Item No. 23546) by GC- or LC-MS. Tasimelteon is a melatonin (MT) receptor agonist.{38574} It selectively binds MT1 and MT2 receptors (Kis = 0.304 and 0.069 nM, respectively, in NIH3T3 cells expressing the recombinant human receptors) over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of non-24-hour sleep-wake disorder.

• Artikelnummer: CAY31771-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31771-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung