Tebufenozide, CAS 112410-23-8

Formulation: A solid

Formal Name: 3,5-dimethyl-1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide, benzoic acid

Purity: ≥95%

Formula Markup: C22H28N2O2

Formula Weight: 352,5

Shelf life (days): 1460

CAS Number: 112410-23-8

Notes: Tebufenozide is an insecticide that acts as a non-steroidal agonist of the insect ecdysone receptor (EcR; IC50 = 0.85 nM in a cell-free preparation of C. suppressalis integument).{41749} It induces a premature molt and is lethal to S. litura third instar larva (LD50 = 0.33 µM per larva).{41749,41750} It also inhibits P-glycoprotein (P-gp), also known as multidrug resistance protein 1 (MDR1), activity in LLC-PK1 porcine kidney epithelial cells expressing human P-gp (IC50 = 21.5 µM).{41751} Tebufenozide has low toxicity in mammals, birds, and most aquatic species, but it dose-dependently decreases colony formation and induces apoptosis and cell cycle arrest in HeLa cells when used at concentrations ranging from 50 to 200 µg/ml.{41752,41753} Formulations containing tebufenozide have been used as insecticides, miticides, sex attractants, and/or feeding stimulants in agricultural, aquatic, and residential areas.

• Artikelnummer: CAY24055-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24055-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK