Formulation: A crystalline solid
Formal Name: N-[(3R)-tetrahydro-3-furanyl]-adenosine
Purity: ≥95%
Formula Markup: C14H19N5O5
Formula Weight: 337,3
Shelf life (days): 1460
CAS Number: 204512-90-3
Notes: Tecadenoson is an adenosine A1 receptor agonist (Ki = 6.5 nM).{48729} It is selective for adenosine A1 over A2 receptors (Ki = 2,315 nM). Tecadenoson prolongs stimulus-His bundle potential (SH) intervals in isolated perfused guinea pig hearts (EC50 = 40.6 nM). In vivo, tecadenoson induces PR interval prolongation in anesthetized guinea pigs (ED50 = 0.9 μg/kg) and reduces heart rate in anesthetized rats in a dose-dependent manner, without affecting blood pressure.