Formulation: A solid
Formal Name: 3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Purity: ≥98%
Formula Markup: C7H8N4O2
Formula Weight: 180,2
Shelf life (days): 1460
CAS Number: 58-55-9
Notes: Theophylline is a methylxanthine alkaloid that is a competitive inhibitor of phosphodiesterase (PDE; Ki = 100 µM).{41252} It is also a non-selective antagonist of adenosine A receptors (Ki = 14 µM for A1 and A2).{41253} Theophylline induces relaxation of feline bronchiole smooth muscle precontracted with acetylcholine (EC40 = 117 µM; EC80 = 208 µM).{41254} Formulations containing theophylline have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).