Thrombin Receptor Peptide Ligand (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: L-alanyl-L-phenylalanyl-L-leucyl-L-alanyl-L-arginyl-L-alanyl-L-alanine, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C33H54N10O8 • XCF3COOH

Formula Weight: 718,8

Shelf life (days): 1460

Notes: Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 µM to inhibit platelet aggregation in vitro).{39777} It inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide (TRAP; Item No. 24125) in vitro when used at a concentration of 32 µM but does not affect platelet aggregation induced by ADP or collagen. It also inhibits thrombin- and TRAP-induced proliferation of vascular smooth muscle cells (VSMCs).{39779} Thrombin receptor peptide ligand (100 µmol/kg bolus, i.v., plus 900 µmol/kg infusion) inhibits arterial thrombosis in a rabbit model of partial carotid artery occlusion without increasing bleeding time.{39778}

• Artikelnummer: CAY24995
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24995-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK