Thyrotropin-Releasing Hormone, CAS 24305-27-9

Formulation: A crystalline solid

Formal Name: 5-oxo-L-prolyl-L-histidyl-L-prolinamide

Purity: ≥98%

Formula Markup: C16H22N6O4

Formula Weight: 362,4

Shelf life (days): 1460

CAS Number: 24305-27-9

Notes: Thyrotropin-releasing Hormone (TRH) is a tropic hormone that stimulates release of thyroid-stimulating hormone (TSH) and prolactin.{41462} It binds to the human TRH receptor (TRHR) expressed in CHO cells and to rat TRHR in rat brain membranes (IC50s = 25 and 198 nM, respectively).{41463,41464} TRH (1 μM) decreases polyphosphoinositide and increases arachidonic and oleic acid diacylglycerol incorporation into lipids of GH3 rat pituitary tumor cells.{41465} In vitro, it dose-dependently increases TSH release from rat anterior pituitary slices and prolactin release from cultured anterior pituitary cells.{41466,41467} In vivo, TRH (0.01 mg/kg) increases TSH and prolactin plasma levels in rats.{41462}

• Artikelnummer: CAY22917-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22917-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK