Formulation: A solid
Formal Name: (5E)-10,11-dihydro-5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-10-ol
Purity: ≥90%
Formula Markup: C19H21NO
Formula Weight: 279,4
Shelf life (days): 1460
CAS Number: 47132-16-1
Notes: trans-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants amitriptyline (Item No. 15881) and nortriptyline (Item No. 15904).{61943,61944} It is formed from amitriptyline and nortriptyline by the cytochrome P450 (CYP) isoform CYP2D6.{61943} trans-10-hydroxy Nortriptyline inhibits norepinephrine reuptake in rat cortical slices and isolated human plasma (EC50s = 160 and 176 nM, respectively).{61944}