Formulation: A lyophilized powder
Formal Name: L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagine, trifluoroacetate salt
Purity: ≥95%
Formula Markup: C34H56N10O9 • XCF3COOH
Formula Weight: 748,9
Shelf life (days): 1460
Notes: TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1).{40527} It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 µM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.{40526}