Formulation: A crystalline solid
Formal Name: 6-phenyl-2,4,7-pteridinetriamine
Purity: ≥98%
Formula Markup: C12H11N7
Formula Weight: 253,3
Shelf life (days): 1460
CAS Number: 396-01-0
Notes: Triamterene is an inhibitor of the epithelial sodium channel (ENaC; IC50 = 4.5 µM for the rat channel).{33172} In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases potassium secretion in adrenalectomized rats.{57562} Formulations containing triamterene have been used in the treatment of edema. This product is also available as an analytical reference standard (Item No. 22486).