Trimethobenzamide (hydrochloride), CAS 554-92-7

Formulation: A solid

Formal Name: N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-benzamide, monohydrochloride

Purity: ≥95%

Formula Markup: C21H28N2O5 • HCl

Formula Weight: 424,9

Shelf life (days): 1460

CAS Number: 554-92-7

Notes: Trimethobenzamide is a dopamine D2 receptor antagonist and antiemetic.{41366} It prevents emesis induced by the dopamine agonist apomorphine (Item No. 16094) in dogs when used at a dose of 20 mg/kg and stimulates contraction of isolated guinea pig ileum (ED50 = 8.7 μg/mL).{41368} Trimethobenzamide (20 mg/kg) decreases apomorphine-induced pecking responses in pigeons by 20% and increases the latent period of pecking from 4.3 to 8 minutes.{41367} Trimethobenzamide (6.7 g/kg per day for 2 weeks) enhances compensation and decreases recovery time from 70 to 32 weeks in unilaterally labyrinthectomized cats, a model of vestibular injury.{41369} Formulations containing trimethobenzamide have been used to treat nausea and vomiting.

• Artikelnummer: CAY24145-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24145-500
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK