TRPM4-IN-5, CAS 351424-20-9

Formulation: A solid

Formal Name: 4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]-benzoic acid

Purity: ≥98%

Formula Markup: C15H11Cl2NO4

Formula Weight: 340,2

Shelf life (days): 1460

CAS Number: 351424-20-9

Notes: TRPM4-IN-5 is an inhibitor of transient receptor potential melastatin 4 (TRPM4; IC50 = 1.5 µM in HEK293 cells expressing TRPM4).{66072} It is selective for TRPM4 over TRPM5 at 10 µM and TRPM7, TRPM8, transient receptor potential vanilloid 1 (TRPV1), and TRPV6 at 100 µM, as well as a panel of 17 other ion channels and receptors at 10 µM. TRPM4-IN-5 (50 µM) inhibits persistent firing in isolated mouse thalamic slices stimulated with the small conductance calcium-activated potassium channel (KCa2.2/SK2) inhibitor apamin (Item No. 17082).{66073}

• Artikelnummer: CAY36019-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36019-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe