TUG-770, CAS 1402601-82-4

Formulation: A crystalline solid

Formal Name: 4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluoro-benzenepropanoic acid

Purity: ≥98%

Formula Markup: C19H14FNO2

Formula Weight: 307,3

Shelf life (days): 1460

CAS Number: 1402601-82-4

Notes: TUG-770 is an agonist of free fatty acid receptor 1 (FFA1/GPR40; EC50 = 6.16 nM for a response to the full FFA1 agonist TUG-20 in a calcium assay in 1311N1 cells).{37557} It is selective for FFA1 over FFA2 (EC50 = 933 nM in a BRET assay). It reduces glucose levels in mice in an intraperitoneal glucose tolerance test in a dose-dependent manner with a maximal reduction at a dose of 50 mg/kg. It also reduces glucose levels in an oral glucose tolerance test in a diet-induced obesity mouse model for at least 29 days.

• Artikelnummer: CAY22131-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22131-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK