Tulobuterol (hydrochloride), CAS 56776-01-3

Formulation: A solid

Formal Name: 2-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-benzenemethanol, monohydrochloride

Purity: ≥98%

Formula Markup: C12H18ClNO • HCl

Formula Weight: 264,2

Shelf life (days): 1460

CAS Number: 56776-01-3

Notes: Tulobuterol is a long-acting agonist of the β2-adrenergic receptor (β2-AR).{69008} It binds to the bovine skeletal muscle β2-AR (Kd = 0.13 µM). Transdermal administration of tulobuterol (6 and 12 mg/kg) decreases total leukocyte infiltration into the bronchoalveolar lavage fluid (BALF) in a mouse model of allergic asthma induced by ovalbumin.{69009} It also inhibits rhinovirus replication in infected primary human tracheal epithelial cells when used at a concentration of 0.1 µM, an effect that can be reversed by the β2-AR antagonist ICI 118551 (Item No. 15591).{69010} Formulations containing tulobuterol have been used in the treatment of asthma.

• Artikelnummer: CAY35562-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35562-5
• Green Labware: Nein
• Verpackungseinheit: 5 g
• Mengeneinheit: STK
• Methode: Reinstoffe