Formulation: A solid
Formal Name: 4-(2-aminoethyl-1,1,2,2-d4)-phenol, monohydrochloride
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C8H7D4NO • HCl
Formula Weight: 177,7
Shelf life (days): 1460
CAS Number: 1189884-47-6
Notes: Tyramine-d4 is intended for use as an internal standard for the quantification of tyramine (Item No. 18601) by GC- or LC-MS. Tyramine is a tyrosine-derived endogenous and dietary monoamine and trace amine-associated receptor 1 (TAAR1) agonist.{24428,22581,30099} It activates TAAR1 (EC50s = 0.08, 0.69, and 2.26 µM for rat, mouse, and human-rat chimera receptors, respectively).{24428} Tyramine also inhibits the release of norepinephrine and dopamine in isolated rat caudate nucleus (IC50s = 40.6 and 119 nM, respectively).{26354}