Urocortin II (human) (trifluoroacetate salt), CAS 398001-88-2

Urocortin II (human) (trifluoroacetate salt), CAS 398001-88-2
Artikelnummer
CAY24746-1
Verpackungseinheit
1 mg
Hersteller
Cayman Chemical

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Formulation: A lyophilized powder

Formal Name: L-isoleucyl-L-valyl-L-leucyl-L-seryl-L-leucyl-L-α-aspartyl-L-valyl-L-prolyl-L-isoleucylglycyl-L-leucyl-L-leucyl-L-glutaminyl-L-isoleucyl-L-leucyl-L-leucyl-L-α-glutamyl-L-glutaminyl-L-alanyl-L-arginyl-L-alanyl-L-arginyl-L-alanyl-L-alanyl-L-arginyl-L-α-glutamyl-L-glutaminyl-L-alanyl-L-threonyl-L-threonyl-L-asparaginyl-L-alanyl-L-arginyl-L-isoleucyl-L-leucyl-L-alanyl-L-arginyl-L-valylglycyl-L-histidyl-L-cysteine, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C194H339N63O54S • XCF3COOH

Formula Weight: 4450,2

Shelf life (days): 1460

CAS Number: 398001-88-2

Notes: Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF, urocortin (Item No. 24745), urocortin III (Item Nos. 24749 / 24750), frog sauvagine, and piscine urotensin I.{38848} Human urocortin II shares 34, 43, and 37-40% sequence homology with rat and human CRF, human urocortin (Item No. 24744), and human urocortin III (Item No. 24748). Urocortin II increases cell shortening and accelerates relaxation of rabbit ventricular myocytes in a time- and concentration-dependent manner. In vivo, urocortin reduces arterial blood pressure in normotensive and spontaneously hypertensive rats via peripheral CRF2 receptor agonism. It induces dose-dependent tachycardia and hypotension in rats when administered at doses of 3 and 30 pmol/kg.{38849} Urocortin (10 and 20 μg/kg) also reduces the visceral pain response to colorectal distension in conscious rats and delays gastric emptying in mice.{38848,38850}
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Artikelnummer CAY24746-1
Hersteller Cayman Chemical
Hersteller Artikelnummer 24746-1
Green Labware Nein
Verpackungseinheit 1 mg
Mengeneinheit STK
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