Formulation: A solid
Formal Name: 7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline-7,7,9,9-d4
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C13H9D4N3
Formula Weight: 215,3
Shelf life (days): 1460
CAS Number: 2183239-01-0
Notes: Varenicline-d4 is intended for use as an internal standard for the quantification of varenicline (Item No. 15030) by GC- or LC-MS. Varenicline is a full agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs; EC50 = 18 µM) and a partial agonist of α4β2 subunit-containing nAChRs (EC50 = 2.3 µM).{22776} Formulations containing varenicline have been used as aids in smoking cessation.