Verapamil (hydrochloride), CAS 152-11-4

Formulation: A crystalline solid

Formal Name: α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile, monohydrochloride

Purity: ≥98%

Formula Markup: C27H38N2O4 • HCl

Formula Weight: 491,1

Shelf life (days): 1460

CAS Number: 152-11-4

Notes: Verapamil is the prototypical blocker of L-type calcium channels that produces excitation-contraction uncoupling in cardiac muscle by preventing the slow-inward current of calcium ions.{22485} Verapamil can also block calcium fluxes in vascular smooth muscle. It has both peripheral and coronary vasodilator effects (IC50 = 0.38 μM in guinea pig aortic strip) and has been used to control hypertension, angina, cardiac arrhythmia, and vascular headaches.{22481,22479,22478} Verapamil has also been used in cell biology as an inhibitor of drug efflux pump proteins such as P-glycoprotein, which are often over-expressed in certain tumor cell lines.{20755}

• Artikelnummer: CAY14288-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 14288-10
• Green Labware: Nein
• Verpackungseinheit: 10 g
• Mengeneinheit: STK
• Methode: Reinstoffe