WAY-200070, CAS 440122-66-7

Formulation: A crystalline solid

Formal Name: 7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol

Purity: ≥98%

Formula Markup: C13H8BrNO3

Formula Weight: 306,1

Shelf life (days): 1460

CAS Number: 440122-66-7

Notes: WAY-200070 is a potent and selective agonist of estrogen receptor β (ERβ; IC50s = 2 and 187 nM for human full-length ERβ and ERα, respectively).{39360} WAY-200070 (30 mg/kg, s.c. in mice) induces nuclear translocation of ERβ and increases c-fos activation and dopamine levels in the striatum four hours after administration.{39359} At the same dose, it decreases depressive-like behavior in the tail suspension test. It has anxiolytic effects in mice using the four-plate and stress-induced hyperthermia tests and in zebrafish larvae using a light-dark choice behavior test.{39359,39358} In addition, WAY-200070 improves glucose and insulin sensitivity in mouse models of diabetes.{39357}

• Artikelnummer: CAY23323-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23323-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK