Formulation: A residue
Formal Name: cyclo[glycyl-L-tryptophyl-L-prolylglycyl-L-valylglycyl-(βR)-β-hydroxy-3-(3-methyl-2-butenyl)-L-tyrosyl]
Purity: ≥95%
Formula Markup: C41H52N8O9
Formula Weight: 800,9
Shelf life (days): 730
CAS Number: 151928-32-4
Notes: WIN 66,306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes.{60290} It binds to NK1 and NK2 receptors (Kis = 8 and 3.8 µM, respectively, for the human receptors) and inhibits contractions induced by substance P (Item No. 24035) in isolated guinea pig ileum in a concentration-dependent manner.