WKYMVm (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tryptophyl-L-lysyl-L-tyrosyl-L-methionyl-L-valyl-D-methioninamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C41H61N9O7S2 • XCF3COOH

Formula Weight: 856,1

Shelf life (days): 1460

Notes: WKYMVm is a synthetic peptide agonist of formyl peptide receptor 1 (FPR1) and FPR2, which was previously known as formyl peptide receptor-like 1 (FPRL1).{54895,54897,54896} It induces calcium mobilization in ETFR rat basophilic leukemia cells transfected with FPR1 or FPR2 when used at a concentration of 0.1 nM.{54895} WKYMVm stimulates chemotaxis of monocytes, dendritic cells, and natural killer (NK) cells, as well as induces superoxide production in monocytes and neutrophils, in vitro.{54896} In vivo, WKYMVm (8 mg/kg) reverses mucosal destruction, decreases in body weight, and colonic shortening in a mouse model of colitis induced by dextran sulfate (sodium salt) (DSS; Item No. 23250). Topical application of WKYMVm stimulates angiogenesis and accelerates re-epithelialization and granulation tissue formation in a rat model of diabetic cutaneous wounds.{54897}

• Artikelnummer: CAY33589-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33589-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK