Xestospongin C, CAS 88903-69-9

Formulation: A clear film

Formal Name: [1R-(1R,4aR,11R,12aS,13S,16aS,23R,24aS)]-eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b1]dipyridine

Purity: ≥90%

Formula Markup: C28H50N2O2

Formula Weight: 446,7

Shelf life (days): 1460

CAS Number: 88903-69-9

Notes: Xestospongin C is a marine natural product which was first isolated from Pacific basin sponges, and noted to have vasodilatory properties.{9844} Xestospongin C antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Inositol phosphates are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores. Xestospongin C blocks the increase in intracellular calcium in vascular smooth muscle cells completely at a concentration of 25 µM.{9845} Xestospongin C also inhibits the sarcoplasmic reticulum Ca2+ ATPase pump at concentrations of 700 nM.{10509}

• Artikelnummer: CAY64950-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 64950-10
• Green Labware: Nein
• Verpackungseinheit: 10 µg
• Mengeneinheit: STK