Yamogenin, CAS 512-06-1

Formulation: A solid

Formal Name: (3β,25S)-spirost-5-en-3-ol

Purity: ≥98%

Formula Markup: C27H42O3

Formula Weight: 414,6

Shelf life (days): 1460

CAS Number: 512-06-1

Notes: Yamogenin is a steroidal sapogenin that has been found in fenugreek (T. foenum graecum) and has diverse biological activities.{64666,64667} It inhibits activation of the liver X receptor (LXR) induced by the LXRα and LXRβ agonist T0901317 (Item No. 71810) in HepG2 cells in a reporter assay when used at concentrations of 5 or 10 µM.{64666} Yamogenin (10 µM) decreases triglyceride levels in primary mouse hepatocytes. It is cytotoxic to HaCaT keratinocytes, as well as HeLa cervical and SKOV3 ovarian cancer cells (IC50s = 16.4, 19.6, and 23.9 µg/ml, respectively).{64667}

• Artikelnummer: CAY36008-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36008-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe