YE 120, CAS 383124-82-1

Formulation: A solid

Formal Name: 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-propanedinitrile

Purity: ≥98%

Formula Markup: C16H9Cl2N3O

Formula Weight: 330,2

Shelf life (days): 1460

CAS Number: 383124-82-1

Notes: YE 120 is an agonist of G protein-coupled receptor 35 (GPR35) with an EC50 value of 32 nM in a dynamic mass redistribution (DMR) assay using HT-29 cells.{49435} It induces β-arrestin translocation in Tango GPR35-bla U2OS cells (EC50 = 10.2 µM). YE 120 (10 µM) promotes wound closure in YAMC colonic epithelial and IEC-6 intestinal epithelial cell monolayers, an effect that can be blocked by the GPR35 antagonist CID-2745687 (Item No. 12046).{49436}

• Artikelnummer: CAY29720-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29720-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK