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KLRK1 Recombinant Protein
KLRK1 Recombinant Protein
Artikelnummer
AVIOPCD00716-50
Verpackungseinheit
50µg
Hersteller
Aviva Systems Biology
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Conjugation: Unconjugated
Description of Target: Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1.
Molecular Weight: 20kDa
Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Protein Name: NKG2-D type II integral membrane protein
Protein Size: Recombinant
Purity: > 90%
Source: E.coli
Tag: N-terminal His Tag
Description of Target: Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1.
Molecular Weight: 20kDa
Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Protein Name: NKG2-D type II integral membrane protein
Protein Size: Recombinant
Purity: > 90%
Source: E.coli
Tag: N-terminal His Tag
| Artikelnummer | AVIOPCD00716-50 |
|---|---|
| Hersteller | Aviva Systems Biology |
| Hersteller Artikelnummer | OPCD00716-50UG |
| Green Labware | Nein |
| Verpackungseinheit | 50µg |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine) |
| Methode | Western Blotting, Positive Control, SDS-PAGE |
| Human Gene ID | 27007 |
| Wirt | Escherichia Coli |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
