Peanut Lectin (FITC)

Peanut Lectin (FITC)
Artikelnummer
GTX01508-1
Verpackungseinheit
1 mg
Hersteller
GeneTex

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Species: Arachis hypogaea

Product Description: Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells.

Application Note: ICC/IF: 1:250-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Specificity/Sensitivity: Carbohydrate-Binding Specificity of Peanut Lectin : Galβ1, 3 GalNAc>>GalNAc>Gal

Form: Liquid

Buffer (with preservative): 10mM Bicarbonate (pH8.2), 150mM NaCl, 0.1mM Calcium Chloride, 0.05% Sodium azide.

Concentration: 5 mg/ml (Please refer to the vial label for the specific concentration.)

Background: Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells. Peanut lectin contains one atom of Ca++ and Mg++ per unit.

Inhibiting/Eluting sugars: 200 mM GalactoseCarbohydrate-Binding Specificity of PNA: Galβ1, 3 GalNAc>>>>>GalNAc>Gal

Region Sequence: Native Protein

ExpressionSystem: Native Protein

Purification: Purified by affinity chromatography followed by gel filtration chromatography

Conjugation: FITC

Full Name: Peanut agglutinin lectin, Arachis hypogaea

Mehr Informationen
Artikelnummer GTX01508-1
Hersteller GeneTex
Hersteller Artikelnummer GTX01508-1
Green Labware Nein
Verpackungseinheit 1 mg
Mengeneinheit STK
Methode Immunofluorescence, Immunocytochemistry
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