1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA (ammonium salt), CAS 799268-65-8

Formulation: A solid

Formal Name: (5Z,8Z,11Z,14Z)-eicosatetraenoic acid, (2R)-hydroxy-3-(phosphonooxy)propyl ester, monoammonium salt

Purity: ≥95%

Formula Markup: C23H38O7P • NH4

Formula Weight: 475,6

Shelf life (days): 180

CAS Number: 799268-65-8

Notes: 1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol (1-AG; Item No. 62150).{10322} 1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM.{43503} It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS.{43504} It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.{43505}

• Artikelnummer: CAY10019-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10019-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK