Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 3-(octadecyloxy)-1-(dihydrogen phosphate)-1,2-propanediol
Purity: ≥95%
Formula Markup: C21H45O6P
Formula Weight: 424.6
CAS Number: 52977-29-4
Notes: 1-Octadecyl-2-hydroxy-sn-glycero-3-phosphate (1-Octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.{15053}
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