1-Oleyl-2-hydroxy-sn-glycero-3-PA (sodium salt)

Formulation: A crystalline solid

Formal Name: 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphate, monosodium salt

Purity: ≥95%

Formula Markup: C21H44O6P • Na

Formula Weight: 446,5

Shelf life (days): 730

Notes: 1-Oleyl-2-hydroxy-sn-glycero-3-PA (1-Octadecyl LPA) is a LPA analog containing stearyl alcohol at the sn-1 position. LPA binds to one of five different G protein-linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has platelet aggregating activity with an EC50 value of 9 nM versus an EC50 value of 177 nM for 1-octadecanoyl LPA.{15053}

• Artikelnummer: CAY10010291-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10010291-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK