(±)10(11)-EpDPA, CAS 895127-65-8

(±)10(11)-EpDPA, CAS 895127-65-8
Artikelnummer
CAY10471-25
Verpackungseinheit
25 µg
Hersteller
Cayman Chemical

Verfügbarkeit: wird geladen...
Preis wird geladen...
Formulation: A solution in ethanol

Formal Name: (±)-(4Z,7Z)-9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid

Purity: ≥95%

Formula Markup: C22H32O3

Formula Weight: 344,5

Shelf life (days): 365

CAS Number: 895127-65-8

Notes: Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA; Item No. 90310) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 µM.{29509,29508} (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.{29509,26641}
Mehr Informationen
Artikelnummer CAY10471-25
Hersteller Cayman Chemical
Hersteller Artikelnummer 10471-25
Green Labware Nein
Verpackungseinheit 25 µg
Mengeneinheit STK
Produktinformation (PDF) Download
MSDS (PDF) Download