(±)10(11)-EpDPA, CAS 895127-65-8

(±)10(11)-EpDPA, CAS 895127-65-8
Artikelnummer
CAY10471-500
Verpackungseinheit
500 µg
Hersteller
Cayman Chemical

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Formulation: A solution in ethanol

Formal Name: (±)-(4Z,7Z)-9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid

Purity: ≥95%

Formula Markup: C22H32O3

Formula Weight: 344,5

Shelf life (days): 365

CAS Number: 895127-65-8

Notes: Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA; Item No. 90310) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 µM.{29509,29508} (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.{29509,26641}
Mehr Informationen
Artikelnummer CAY10471-500
Hersteller Cayman Chemical
Hersteller Artikelnummer 10471-500
Green Labware Nein
Verpackungseinheit 500 µg
Mengeneinheit STK
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