(±)11(12)-EpETE, CAS 504435-15-8

Formulation: A solution in ethanol

Formal Name: (±)11,12-epoxy-5Z,8Z,14Z,17Z- eicosatetraenoic acid

Purity: ≥98%

Formula Markup: C20H30O3

Formula Weight: 318,5

Shelf life (days): 730

CAS Number: 504435-15-8

Notes: Eicosapentaenoic acid (EPA; Item No. 90110) is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms.{18671} The major product of this epoxygenase pathway, (±)17(18)-EpETE (Item No. 50861), relaxes vascular and airway smooth muscle by binding large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits.{9825,18669,18670} (±)11(12)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.{18671,18672} The biological actions and physiological effects of this epoxide remain to be determined.

• Artikelnummer: CAY10462-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10462-50
• Green Labware: Nein
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK