11β-13,14-dihydro-15-keto Prostaglandin F2α, CAS 107615-77-0

Formulation: A solution in methyl acetate

Formal Name: 9α,11β-dihydroxy-15-oxo-prost-5Z-en-1-oic acid

Purity: ≥95%

Formula Markup: C20H34O5

Formula Weight: 354,5

Shelf life (days): 365

CAS Number: 107615-77-0

Notes: 11β-13,14-dihydro-15-keto PGF2α is a metabolite of PGD2 (Item No. 12010) in the 15-hydroxy PGDH pathway.{11174,11176} Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11β-PGF2α, as the immediate product, and 11β-13,14-dihydro-15-keto PGF2α in the plasma within 10 minutes.{11174} Homogenates of human lung metabolize PGD2 first to 11β-PGF2α and then to 11β-15-keto-PGF2α in the presence of NAD+, but not 11β-13,14-dihydro-15-keto PGF2α.{11176} Guinea pig liver and kidney homogenates metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α, via 11β-PGF2α, in the presence of NAD+ and NADP+.{11176}

• Artikelnummer: CAY16540-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16540-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK