Formulation: A solution in methyl acetate
Formal Name: (±)12(13)epoxy-9Z-octadecenoic acid
Purity: ≥98%
Formula Markup: C18H32O3
Formula Weight: 296,5
Shelf life (days): 730
Notes: (±)12(13)-EpOME is the 12,13-cis epoxide form of linoleic acid (Item Nos. 90150 / 90150.1 / 21909).{651,59199} It is formed primarily via linoleic acid metabolism by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can contribute to (±)12(13)-EpOME production when pharmacologically induced.{59199} (±)12(13)-EpOME (500 µM) induces mitochondrial dysfunction and cell death in renal proximal tubule epithelial cells.