13,14-dihydro-15-keto Prostaglandin D2-d9, CAS 2738376-77-5

Formulation: A solution in methyl acetate

Formal Name: 9α-hydroxy-11,15-dioxo-prost-5Z-en-1-oic-17,17,18,18,19,19,20,20,20-d9 acid

Purity: ≥99% deuterated forms (d1-d9)

Formula Markup: C20H23D9O5

Formula Weight: 361,5

Shelf life (days): 730

CAS Number: 2738376-77-5

Notes: 13,14-dihydro-15-keto-Prostaglandin D2-d9 (13,14-dihydro-15-keto PGD2-d9) is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGD2 (Item No. 12610) by GC- or LC-MS. 13,14-dihydro-15-keto PGD2 is a metabolite of PGD2 (Item No. 12010) which is formed through the 15-hydroxy PGDH pathway. 13,14-dihydro-15-keto PGD2 was recently identified as a selective agonist for the CRTH2/DP2 receptor.{5248} It also inhibits ion flux in a canine colonic mucosa preparation.{9769} In humans, 13,14-dihydro-15-keto PGD2 is further metabolized to give 11β-hydroxy compounds which have also undergone β-oxidation of one or both side chains. Virtually no 13,14-dihydro-15-keto PGD2 survives intact in the urine.{418,35}

• Artikelnummer: CAY19334-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 19334-50
• Green Labware: Nein
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung