13,14-dihydro-16,16-difluoro Prostaglandin E1, CAS 475992-30-4

Formulation: A solution in methyl acetate

Formal Name: 9-oxo-11α,15S-dihydroxy-16,16-difluoro-prostan-1-oic acid

Purity: ≥98%

Formula Markup: C20H34F2O5

Formula Weight: 392,5

Shelf life (days): 730

CAS Number: 475992-30-4

Notes: Prostaglandin E1 (PGE1) is produced by the metabolism of dihomo-γ-linolenic acid (DGLA) by the cyclooxygenase pathway. PGE1 inhibits platelet aggregation (IC50 = 40 nM){960,4165} and increases vasodilation. 13,14-dihydro-16,16-difluoro PGE1 is an analog of PGE1. 13,14-dihydro PGE1 is a biologically active metabolite of PGE1, inhibiting platelet aggregation with comparable potency to the parent compound.{2126,4165} The addition of two electron-withdrawing fluorine atoms, which should stabilize the molecule against hydrolytic cleavage, may be expected to delay degradation in vivo.{17623}

• Artikelnummer: CAY9000405-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9000405-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK