Formulation: A solution in methyl acetate
Formal Name: 9-oxo-11α,15S-dihydroxy-prostan-1-oic acid
Purity: ≥98%
Formula Markup: C20H36O5
Formula Weight: 356,5
Shelf life (days): 365
CAS Number: 19313-28-1
Notes: 13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.{4168,182} It is an inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 31 and 21 nM, respectively.{1607} 13,14-dihydro PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 (Item No. 13010) which has an IC50 value of 40 nM.{960} Also, 13,14-dihydro PGE1 was shown to activate adenylate cyclase in NCB-20 hybrid cells with a Kact value of 668 nM.{1926}