13,14-dihydro Prostaglandin E1-d4

Formulation: A solution in methyl acetate

Formal Name: 9-oxo-11α,15S-dihydroxy-prostan-1-oic-3,3,4,4-d4 acid

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C20H32D4O5

Formula Weight: 360,5

Shelf life (days): 730

Notes: 13,14-dihydro Prostaglandin E1-d4 (13,14-dh PGE1-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dh PGE1 by GC- or LC-mass spectrometry. 13,14-dh PGE1 is an inhibitor of ADP-induced platelet aggregation in human platelet-rich plasma and washed platelets with IC50 values of 31 and 21 nM, respectively.{1607} 13,14-dh PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 of 40 nM.{960} Also, 13,14-dh PGE1 activates adenylate cyclase in NCB-20 hybrid cells with a Kact of 668 nM.{1926}

• Artikelnummer: CAY9000281-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9000281-50
• Green Labware: Nein
• Verpackungseinheit: 50 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung