(±)13(14)-EpDPA, CAS 895127-64-7

Formulation: A solution in ethanol

Formal Name: (±)-(4Z,7Z,10Z)-12-[3-(2Z,5Z)-2,5-octadien-1-yl-2-oxiranyl]-4,7,10-dodecatrienoic acid

Purity: ≥95%

Formula Markup: C22H32O3

Formula Weight: 344,5

Shelf life (days): 365

CAS Number: 895127-64-7

Notes: Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid (DHA; Item No. 90310) epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 µM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models.{29509} (±)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.{26641}

• Artikelnummer: CAY10464-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10464-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK