15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α, CAS 1194396-71-8

Formulation: A solution in ethanol

Formal Name: 6-(nitrooxy)-hexanoic acid, (1S,2E)-3-[(1R,2R,3S,5R)-2-[(2Z)-7-(ethylamino)-7-oxo-2-hepten-1-yl]-3,5-dihydroxycyclopentyl]-1-(2-phenylethyl)-2-propen-1-yl ester

Purity: ≥98%

Formula Markup: C31H46N2O8

Formula Weight: 574,7

Shelf life (days): 365

CAS Number: 1194396-71-8

Notes: 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α (15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2α (Item No. 16810).{62159} It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically administered at a concentration of 0.042%. Topical administration of 15-(6-nitroxylhexanoyl)-17-phenyl trinor PGF2α (0.14%) reduces intraocular hypertension (IOP) in a rabbit model of hypertonic saline-induced transient ocular pressure. It also reduces IOP in a cynomolgus monkey model of laser-induced ocular hypertension when administered topically at a concentration of 0.042%.

• Artikelnummer: CAY32791-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 32791-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK