Formulation: A solution in methyl acetate
Formal Name: 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid
Purity: ≥95%
Formula Markup: C20H28O3
Formula Weight: 316,4
Shelf life (days): 730
CAS Number: 87893-55-8
Notes: 15-deoxy-Δ12,14-Prostaglandin J2 (15-deoxy-Δ12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 value of 2 µM in a murine chimera system.{1428,1424} 15-deoxy-Δ12,14-PGJ2 is more potent than PGD2, Δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.{1428}