15-deoxy-Δ12,14-Prostaglandin J2-d9

Shelf life (days): 730.0

Formulation: A solution in methyl acetate

Formal Name: 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid-d9

Purity: ≥99% deuterated forms (d1-d9)

Formula Markup: C20H19D9O3

Formula Weight: 325.5

Notes: 15-deoxy-Δ12,14-Prostaglandin J2-d9 (15-deoxy-Δ12,14-PGJ2-d9) is intended for use as an internal standard for the quantification of 15-deoxy-Δ12,14-PGJ2 (Item No. 18570 / 18570.1) by GC- or LC-MS. 15-deoxy-Δ12,14-PGJ2 is formed from PGD2 (Item No. 12010) by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 value of 2 µM in a murine chimera system.{1428,1424} 15-deoxy-Δ12,14-PGJ2 is more potent than PGD2, Δ12-PGJ2 (Item No. 18550), and PGJ2 (Item No. 18500) in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.{1428}

• Artikelnummer: CAY19347
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 19347-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung