Formulation: A solution in ethanol
Formal Name: 9-oxo-11α,15R,19R-trihydroxy-prost-13E-en-1-oic acid
Purity: ≥98%
Formula Markup: C20H34O6
Formula Weight: 370,5
Shelf life (days): 365
Notes: 19(R)-Hydroxylated prostaglandins occur in µg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R).{7578} 19(R)-Hydroxylated prostaglandins are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate.{2390} The 15(R)-hydroxy epimer of these 19-hydroxylated prostaglandins is the inverse or “unnatural” isomer at C-15. The biological role of 19(R)-hydroxylated prostaglandins is not well established. In the E-series, 19(R)-hydroxylation has been identified with EP2 receptor subtype selectivity.{1441}