15(R)-Prostaglandin D2, CAS 59894-05-2

Formulation: A solution in methyl acetate

Formal Name: 9α,15R-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid

Purity: ≥98%

Formula Markup: C20H32O5

Formula Weight: 352,5

Shelf life (days): 365

CAS Number: 59894-05-2

Notes: Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor.{3128} However, in certain leukocytes and other immune cells, a second PGD2 receptor referred to as the CRTH2 or DP2 receptor has been cloned and characterized.{9767,9769} 15(R)-15-methyl PGD2 is a surprisingly potent agonist at the DP2 receptor, being about 5 times more potent than PGD2 itself.{10723} 15(R)-PGD2 has the potential to be produced endogenously as a natural ligand for DP2, unlike the synthetic 15-methyl analogs. In preliminary reports, 15(R)-PGD2 has also been reported to be a potent and selective DP2 receptor agonist.{11220,14546}

• Artikelnummer: CAY10118-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10118-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK